Атлас заболеваний полости рта - Ланге Р.П.
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D: NicopyronВ® (Trommsdorff) F: Pro-DoiВ® (Meram)-Komb. GB: ThylinВ® (Sinclair) I: AlgotrexВ® (Ct) DipiralВ® (Sirt-BBP) NeopiranВ® (Panthox & Burck) NiapanВ® (Chimiphara) NicoreumalВ® (Sit) ReumatosilВ® (Sabo) SupermidoneВ® (Salfa) u. Komb.-Praparate J: BontoramВ® (Sanwa) Chillos-NВ® (Kotani) NiapyrineВ® (Iwaki) NicazolidinВ® (Kissei) NicotinoyfВ® (Nissin) Rhyumapirine NВ® (Nichiiko) SausalВ® (Tokyo Hosei) SeberinВ® (Mohan) TromrheumanВ® (Maruko)
Nifluminsaure 4394-00-7 Antiphlogisticum;
(Nifluril; Antirheumaticum Niflumic acid)
2-[3-(trifluoromethyl)aniIino]nicotinic acid
Nifluminsaure - Nifuratel N 635
nh2
oc • &
2-Chlor-
nicotinsaure
3-Trifluormethyl-
anilin
^Y'COOH
St^nh
jb
Nitluminsaure
I^YC00H t A
N NH? ^^СГз
N NH2
2-Amtno-
nicotinsaure
K2C03/Cu
3-Brom-l-
trifluormethyl-
benzol
Nitluminsaure
DOT 4, 82 (1968).
a DBP 1470014 (Labs. U.P.S.A.; Anm. 10.12.1964; GB-Prior. 19.12.1963, 25.3.1964). Belg-P 657 266 (Labs. U.P.S.A.; Am. 19.12.1964; GB-Prior. 19.12.1963; 25.3.1964). USP 3 415 834 (U.P.S.A.; ert. 10.12.1968; GB-Prior. 19.12.1963, 25.3.1964). b USP 3 337 570 (Schering Corp.; ert. 22.8.1967; Prior. 23.10.1965).
D: ActolВ® (Heyden) F: NiflurilВ® (Upsa)
Nifuratel
4936-47-4
Chemotherapeuticum
(Trichomonacid)
5-[(methylthio)methyl]-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
CL-CHf Epichlorhydrin
OH
I
HS-РЎРќР· -* CI-CH2-CH-CH2-S-CH3
Methyl- 1-Chlor-3-metbylthio-2-
mercaptan propanol
h2n-nh2 в– H20 Hydra* m-Hydrat
H2N--NH-CH2-CH-CH2-S-CH3
(3-Methylthio-2-hydroxy-
propyU-hydrazin
0ClOC:hs); Diethyl-carbonat
0
h2n-nA0
4
CH2-S-CH3
3-Amino-5-(methylthio-
methyD-Z-l^-oxazolidon
o2n_A^cho
5-Nitrofurfural
o2nxВ°vch-n-nA0
\J V_(
CH2-S-CH3
Belg-P 635 608 (Polichimica SAP; Anm. 30.7.1963; I-Prior. 1.8.1962). GB-P 969 126 (Polichimica; Anm. 25.10.1962; 1-Prior. 1.8.1962).
D: InimurВ® (ICN)
F: Mycomnes (Fumouze)-Komb. OmnesВ® (Fumouze)
GB: MagmilorВ® (Calmic) I: MacmirorВ® (Poli)
636 N Nifuroxazid - Nifurprazin - Nifurtimox
Nifuroxazid
965-52-6
Chemotherapeuticum
p- hydroxybenzoic acid 5-nitrofurfurylidene hydrazide
H2N-NH2 ♦ H3CO-C -o- Oh
0
Hydrazin 4-Hydroxy benzoe-
sauremethylester
4-Hydroxybenzoesaure-
hydrazid
5-Nitrofurfural
O2N
CH = N-NH-C
Рћ
Nifuroxazid
OH
FP 1327 840 (Lab. Robert et Carriere; Anm. 10.4.1962).
FP-M 1 427 (Lab. Robert et Сагпёге; Anm. 12.7.1961).
D: PentofurylВ® (Karlspharma) F: ErcefurylВ® (Robert et Carriere)
MucifuralВ® (Robert et Carriere)
Nifurprazin 1614-20-6 Chemotherapeuticum
24998-17-2 Hydrochlorid
3-amino-6-[2-(5-nitro-2-furyl)vinyl]pyridazine
5-Nitrofurfural 3-Acetamido-6-methyl-
pyridazin
Nifurprazin
DOT 4,104(1968).
DBP 1273 535 (Boehringer Mannh.; Anm. 28.3.1962).
D: CarofurВ® (Boehringer Mannh.)
NifurtimOX 23256-30-6 Chemotherapeuticum
{Trypanosomocid)
4-[(5-nitrofurfurylidene)amino]-3-methylthiomorpholine 1,1-dioxide
Nifurtimox - Nifurzid - Nimetazepam N 637
ho-ch2-ch2-sh
2-Mercaptoethanol
Р›
[РєРѕРЅ].
H3C
1,2-Propy-
lenoxid
KHSOt].
HO-CH-CH2
CH3
(2-Hydroxyethyl )-(2-hydroxypropyl)-sulfid
Рћ S
2-Methyi-
1,4-oxathian
Wasserstoff-per ox id
Рћ so2
yj
H3C
2-Methyl-
1.4-oxathian-
4.4-dioxid
H2N-N SO* — H3C
4-Amino-3-methyl-tetrahydro -1/-thiazin-1,1-dioxid
OjN^CL CHO
XjT
02N^,0v^CH = N-N// S02
лТ у;
H3C Nifurtimox
DOT 7,193(1971).
DBP 1170957(Bayer; Anm. 23.11.1962). D: LampitВ® (Bayer)
Nifurzid 39978-42-2 Chemotherapeuticum
5-nitro-2-thiophenecarboxylic acid [3-(5-mtro-2-furyl)allylidene]hydrazide
s 11 0
02N^^-C-NH-NH2 + ohc-ch = ch~^~^no2
5-Nitro-2-thienylcarbon- 3-{2-Nitro-5-fury I)-acrolein saure-hydrazid
DOS 2 200 375 (Lipha; Anm. 5.1.1972; F-Prior. 7.1.1971).
E. Szarvasi, L. Fontaine, A. Betbeder-Matibet, J. Med. Chem. 16,281 (1973). Ausgangsverbindung:
G. Carrara, F. M. Chiancone, V. d’Amato, Gazz. Chim. Ital. 82,652 (1952).
F: RicrideneВ® (Lipha)
Nimetazepam 2011-67-8 Hypnoticum;
Tranquilizer; Anticonvulsivum
l,3-dihydro-l-methy1-7-nitro-5-phenyl-2H-l,4-benzodiazepin-2-one
XT
o2n
4-Nitroanilin
1. HCl/NaNO?
COCH3
2.
COOC2H5 2 a-Benzylacst-essigsaureethyl-ester
XT
43
CH2
COOC2H5
o2n
Phenylbrenztraubensaureethylester-4- rutrophenylhydrazon
638 N Nimetazepam - Nimorazol
C00C2H5
H
e* o2n
•COOH
1РЎРќР°0|25Рћ2/Рљ0Рќ
Dimethylsulfat
-COOH
5-Nitro-3-phenytindol-2-carbonsaureethylester
1-Methyl-5-nitro-3-
phenylmdol-2-carbon-
saure
CH3
i. SOCi2 2 NHj
3- P0CIВ» - o2n
NaBH< /BF3-Ole;H5l,i
2-Aminomethyt-1 -methyl -E - nitre - 3 - phenyl tndol
РЎРіРћСЌ/РЎРќР·РЎРћРћРќ I O2N
Nimetazepam
DOT 13,31 (1977).
USP 3 652 551 (Sumitomo; ert. 28.3.1972; J-Prior. 1.12.1967, 9.12.1967,14.12.1967,15.12.1967,
21.12.1967, 28.12.1967,10.1.1968,11.3.1968).
DOS 1 811 830 (Sumitomo; Anm. 29.11.1968; J-Prior. 1.12.1967, 9.12.1967,14.12.1967,15.12.1967,
21.12.1967, 28.12.1967,10.1.1968,11.3.1968).
DOS 1816046 (Sumitomo; Anm. 20.12.1968; J-Prior. 25.12.1967, 9.4.1968).
DOS 1817761 (Sumitomo; Anm. 29.11.1968; J-Prior. 1.12,1967, 9.12.1967, 14.12.1967, 15.12.1967, 21.12.1967,28.12.1967,10.1.1968,11.3.1968).
