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.., .. .: , 2008. 224 c.
ISBN 978-5-9704-0578-9
( ): pharmazeutischewirkstoffe1982.djvu
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Primobolan® Depot (Schering)-Onanthat
Primobolan® (SEPPS) USA:
Primobolan®-Depot (SEPPS)-Onanthat Primobolan® Depot (Schering Chem.) Primobolan Depot® (Schering)
Primobolan® Inj. (Nihon Schering)
Primobolan® Depot (Nihon Schering)-Onanthat
Metformin
(Dimethylbiguanid)
657-24-9
1115-70-4
Antidiabeticum
Hydrochlorid
1,1 -dimethylbiguanide
H,c NH
\ //
NH • HCI + N = C-NH-C
/ \
H3C NH2
Dimethylamm- Dicyandiamid Hydrochlorid
H,C NH
3 S //
N -C NH
/ \ //
H3C NH- -C NH-
Metformin - Methadon M 573
DBP 1 023 757 (Heumann & Co.; Anm. 1955) — nur Verfahren. FP-Anm. 2 322 860 (Aron S.A.R.L.; Anm. 5.9.1975).
GB:
Glucophage® retard (Homburg) Toulibor® (Ortscheit) Diabiphage® (Pfizer)-Komb. Glucinan® (Anphar)-Komb. Glucophage® (Lab. Aron) Glucosulfa® (Aron)-Komb. Stagid (Stago)
Glucophage® (Rona) Metiguanide® (Carlo Hrba) Devian® (Pirri)
Diabecron® (Tiber)
Diaberit® (Wassermann)
Diabetosan® (Brocchieri) Diguanil® (Ellea)
Glucadal® (Guidi) Glucophage® (Spemsa) Mellitin® (Chemipharma) Metiguanide® (Erba) Diabetose B® (Nichiiko) Glycoran® (Nippon Shinyaku) Insuloid M® (Ono)
Langer-K® (Kanto)
Melbin® (Sumitomo) Metolmin® (Kodama)
Methadon
76-99-3
1095-90-5
Hydrochloric!
Analgeticum
6-dimethylamino-4,4-diphenyi-3-heptanone ^ 4 rw CH3
- wCN
Oiphenyi-
acetomtril
NaNH2 + Ct-CH-CH2-N
CH, CH3
Natrium-arrnd
1-Dimethylamino-
2-propykchlorid
Och2-ch-n4 CH3 CH3
4-Dimethytamino-2,2-diphenyl valeronitnl (Methadon nitril)
1. C?H?Mg6r
гн2о
1 Ethylmagrwswm-bromid
C0-C2Ht y CH3
s / 3
СН-,—CH—N
2 I \ CH3 CH3
(±)-Methadon
(*)-W«msaure
(-)-Methadon
DBP 865 314 (Farbw. Hoechst; Anm. 1941).
DBP 870 700 (Farbw. Hoechst; Anm. 1942).
DBP 890 506 (Farbw. Hoechst; Anm. 1944).
G. Ehrhart, M. Bockmiihl; Justus Liebigs Ann. Chem. 561, 52 (1948). Altemativ-Verfahren zur Razematspaltung:
USP 2 644 010 (Merck & Co.; ert. 1953; Anm. 1947).
USP 2 983 757 (Abbott; ert. 1961;Anm. 1959).
D: L-Polamidon® (Hoechst) Physeptone® (Wellcome)
GB: Physeptone® (Burroughs Wellcome) USA: Dolophine® (Lilly)
I: Eptadone® (Tosi) Methadone Hydrochloride (Lilly)
Mephenon® (Spemsa)
574 M Methallenestril - Methamphetamin
Methallenestril
(Methallenoestril;
Methallenoestrol)
517-18-0
Oestrogen
/1-ethyl-6-mcthoxy-e.a-dimethyl-2-naphthalenepropionic acid
HjCO’
2-Brom-6-methoxy-
naphthalin
Cu2(CN)2
Kupfer(l)-
cyamd
H3C0'
CH3
1. Br —С —COOC2H5 /Zn
1
CMj
2 H;SOt_
) Brornisobuttecsaure-ethyiester/Zink
НзСО'
0 CH3 II I
C-C-COOC2H5
Etbylmagnesiumbromid
H3CO'
H5C2 снз
i 1
C-C-C0OC2H5
он снз
1 KHS04,ie0oc z. Pt/H2 3. Na^C03 ). Kaliumhydro-gersuilat
USP2547123 (A. Horeau;ert. 1951;F-Prior. 1947).
A. Horeau et al., C. R. Acad. Sci. 224, 862 (1947).
A. Horeau et al., Bull. Soc. Chim. Fr. 1948,711; 1955, 955. Ausgangsverbindung:
DOS 2 619 614 (Hoechst; Anm. 4.5.1976).
H5C2
' H3C0‘
СНз !
CH-C-COQH I I
CH3 I
Methallenestril
GB: Vallestril® (Searle)
J: Ercostrol® (Green Cross)
VaiJestril® (Dainippon) USA: Vallestril® (Searle).
Methamphetamin
(Dgsoxyephednn)
537-46-2
51-57-0 Hydrochlorid
Sympathicomimeticum;
Psychostimulans;
Appetitzijgler
(+ )-A,-a-dirnethylphenethylamine
CH,
I
Ch3
/=®\ I нг/ра-с /=\ 1
<\ Л—CH—CH—NH—CH3 —-»• (. Л-СН2-СН-ЫН-СНз
OH
-Ephedrin
Methamphetamin
H. Emde, Helv. Chim. Acta 12,365 (1929).
D: Pervitin® (Temmler)
J: Philopon® (Dainippon)
USA: Desoxyn® (Abbott)
Methampex™ (Lemmon) Obedrin® (Beecham-Massengill)
Methandriol - Methapyrilen M 575
Methandriol 521-10-8 Anabolicum
17a-methylandrost-5-ene-3/3,17/S-diol
Stigmastenn Orthoameisensaure-
IRohorodukt) triethylester
Mycobacterium spec NRRl-B-3805
H5c2o-
1 LICH3
2 IH3C-CQ)20/BF3-(C;Hs)20
I. Methyllithium 2 Acetanhydnd /Bortrifluond-Etherat
H3C-CO-O
Н3С “ CO - O'
,CH3 I
DOS 2 534 911 (Schering AG; Anm. 1.8.1975).
L. Ruzicka et al., Helv. Chim. Acta 18, 1487 (1935).
K. Miescher, W. Klarer, Helv. Chim. Acta 22,962 (1939).
I: Metilandrostendiolo Schering (Schering) J: Megabion®
Metildiolo® (Orma)-Komb. USA: Methostan® (Schering) Sinesex® (Wells) Stenediol® (Organon) Troformone® (Biomedica Foscama)
Methapyrilen 91-8О-5 Antihistaminicum
(Thenylpyramine) ^ 35-23-9 Hydrochlorid
N,A/-dimethyl-Ar-pyrid-2-yl-A/'-2-thenylethylenediarnine
/—N
O-
CH3
NH~CH2-CH2~N
Л/, N- Dimethyl -A/'-(2-pyndyl)-ethylendiamm
г V*1
ii
CH2C1
2-Thienylmethyl-
chlond
CH3
.CH2-CH2-N
NCH3
Methapyrilen
576 M Methapyrilen - Methaqualon - Methazolamid
A. W. Weston, J. Am. Chem. Soc. 69,980 (1947). USP 2 581 868 (Monsanto; ert. 1952; Prior. 1946). Fumarat: GB-P 694 805 (Monsanto; Laufzeit ab 1950; USA-Prior. 1949).
D: Contac® Liquid (Vonora)-Komb. Copyronilum® (Lilly)-Komb. Sedanocf® (Woelm-Pharma) tiffaforte® (Tiffapharm)-Fumarat I: Co-Pyronil (Lilly) USA: Allerest® (Pharmacraft)-Fumarat-Komb. Brexin® (Savage)-Komb. Citra® (Boyle)-Komb. Co-Pyronil® (Dista)-Komb. Ephed-Organidin (Wallace) Excedrin® P.M. (Bristol-Myers)-Fumarat-Komb. Hista®-Clopane® (Lilly)-Komb. Histadyl® E.C. (Lilly)-Fumarat-Komb. Histadyl Fum. (Lilly)-Fumarat Histadyl Pulvules (Lilly)
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