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Synandrotabs® (Pfizer)
Testora® (Alcon)
Testred® (ICN)
Tylosterone® (Lilly) zahlreiche Komb.-Praparate
Methylthiouracil
56-04-2
Schilddrusen-
therapeuticum
6-methyl-2-thiouracil ar6-methyl-2-thio-2,4(l f/,3//)-pyrimidinedione
h2^c^OC2h5
II
0
Acetessigsaure-
ethylester
h2nVc^s
I
NH,
[NaOC2H5]
H3C^N SH H3C^N S
у ^ Ун
он о
Methylthiouracil
590 M Methylthiouracil - Methyprylon - Methysergid
R. List, Justus Liebigs Ann. Chem. 236, 1 (1886).
G. W. Anderson et al., J. Am. Chem. Soc. 67,2197 (1945).
D: Pitufren® comp. (Brunnengraber)-Komb.
Thyreostat® (Herbrand)
F: Frenantol® Comp. (Laroche Navarron)
J: Methiocil® (Chugai) USA: Muracin® (Organon)
Methyprylon
125-64-4
Hypnoticum
3,3-diethyl-5-methyl-2,4-piperidinedione
C2H5
H3C-CO-C-COOC2H5 + Na + HCOOCH3 C2H5
2,2-Diethyl-acetessig -saureethylester
Ameisensaure-
methytester
~C2H5 ''Q COOC2H5 H
2,2- Diethyl-4-hydroxy-
methylen-acetessigsaure-
ethylester
CO'
C2HS
C2H5 [sj COOC2H5
NaX2Hs
4-Aminomethylen-
2,2-diethyl-acet-
essigsi&ureethylester
(5-Ammo-2,2-diettryl-
З-охо-4-pentensaure-
ethylester)
C2H5
H2/Pd-C
3.3-Oiethyl-1,2,3,4-tetrahydropyridin-
2.4-dion
HO-CH.
Xf2b
r4c
1
f]~C2H5
H
3.3-Diethyl-piperidin-
2.4-dion
{Dihyprylone)
P2H5 C2H5
Ыа1HCOOCH3
Ameisensaure-
methylester
H2/Raney-Ni
I N'^O
H
I Methyprylon
DOT 9,245 (1973).
USP 2 680 116 (Hoffmann-LaRoche; ert. 1954; CH-Prior. 1951). DRP 634 284 (Hoffmann-LaRoche; 1935).
USP 2 151 047 (Hoffmann-LaRoche; Prior. 1938).
D: Noludar® (Roche) GB: Noludar® (Roche)
J: Noctan® (Yamanouchi) USA: Noludar® (Roche)
Methysergid
361-37-5
129-49-7
Hydrogenmaleat
Serotoninantagonist;
Migrane-Mittel
zV-[l-(hydroxymethv I) propyl]-1-methyl- D-lysergamide
Methysergid - Metiazinsaure - Meticillin M 591
HO-CH, t
h3c-ch2-ch-nh
1. KNHj in fl. NH3
2.CH,Br
Methylergometrin (s. S. 584)
HO-CH2
h3c-ch2-ch-nh
N-CH3
USP 3113 133 (Sandoz; ert. 3.12.1963; CH-Prior. 18.5.1956).
USP 3 218 324 (Sandoz; ert. 16.11.1965; CH-Prior. 18.5.1956,20.3.1957,16.4.1957,7.3.1958, 11.3.1960).
DBP 1 076137 (Sandoz; Anm. 7.5.1957; CH-Prior. 18.5.1956, 20,3.1957).
D: Deseril-retard® (Sandoz) F: Desemil® (Sandoz)
GB: Deseril® (Sandoz)
Г: Desernl® (Sandoz) USA: Sansert® (Sandoz)
Metiazinsaure
(Acide metiazinique)
13993-65-2
Antiphlogisticum
10-methylphenothiazine-2-acetic acid
s/hn 0 ‘ \_/
sN''N^>n-f'H Schwefel/ I LM3 - Morpholin
CH3
VNV
I
CH,
CH?-с
M
I
CH3
CH2-COOH;
Metiazinsaure
2-Acetyl-10-methyl- _
phenothiazin
GB-P 1 048 680 (Rhone-Poulenc; Anm. 27.10.1965; F-Prior. 29.10.1964, 30.10.1964, 28.12.1964, 24.9.1965).
Ester-Derivate:
USP 3 424 748 (Rhone-Poulenc; ert. 28.1.1969; F-Prior. 22.10.1965, 25.8.1966).
F: Soridermal® (Specia) Soripal® (Specia)
I: Soripal® (Farmitalia)
J:
Roimal® (Nippon Rhodia) Soripal® (Torii)
Meticillin
(Methicillin;
Sodium Methicillin)
61-32-5
7246-14-2
Antibioticum
Na-Salz, Monohydrat
(2,6-dimethoxyphenyl)penicillin o/'6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-l-azabicyclo[3.2.0]heptane-2-carboxylic acid
0CH3
Q^coqh
0CH3
2,6-Dimethoxy-
benzoesaure
Thionyl-
chiond
PCH3
<^Л-С0-С1
OCH3
2,6-Dimethoxy-
benzoylchlorid
pcH3
4 ^co-NH^-ry^
0СНз COOH
or
Meticillin
592 M Meticillin - Meticran - Metixen
USP 2 951 839 (Beecham; ert. 6.9.1960; GB-Prior. 15.7.1959).
D: Cinopenil® (Hoechst)
F: Chibro-Flabelline
(Merck Sharp & Dohme-Chibret) Flabelline® (Delagrange) Penistaph® (Bristol)
GB: Celbenin® (Beecham)
I: Baclyn® (Sierochimica) Celpillina® (Farmitalia) Ellecillina® (Ellea)
Esapenil®B. G. (Boniscontro & G.) Penysol® (Saita)
Sintespen® (Coli)
Staficyn® (Firma)
J: Methocillin® (Meiji)
Staphcillin® (Banyu)
USA: Azapen® (Pfizer)
Celbenin® (Beecham-Massengill) Staphcillin® (Bristol)
Meticran
1084-65-7
Diureticum
6-methylthiochroman-7-sulfonamide 1,1 -dioxide SH
XT
H3C
4-MethyUhio-
phenol
(p-Thioeresol)
+ H2C = CH-C00H
Acrylsaure
[lCtHaUN*0H~
Ж
"CH2 H:SQt д
CH2- COOH .
6-Methylthiachro-
man-i-on
Zr/HCl Oder HjN-NH;/Raney-Ni _
6-Methylthiachroman
Д)
6-Methylthiachro-
man-U-dioxid
CMorsulton-
saure
НзС
o2
XjO
H3C Meticran
FP 1 365 504 (S.I.F.A; Anm. 24.5.1963). F: Fontilix® (Diamant)
J: Arresten® (Nippon Shinyaku)
Metixen 4969-02-2 Antiparkinson-Mittel; (Methixen) 1553-34-0 Hydrochlorid Spasmolyticum 7081 -40-5 Hydrochlorid-Monohydrat
l-methyl-3-(thioxanthen-9-ylmethyl)piperidine
Metixen - Metoclopramid M 593
Thioxanthen Natrium- 3-Chlormethyl- Metixen
amid 1-methylpiperidir>
USP 2 905 590 (The Wander Comp.; ert. 22.9.1959; Prior. 7.5.1958).
D: T remarit® (Wander)
F: Spasmenzyme® (Salvoxyl-Wander)-Komb.
GB: Tremonil® (Wander)
I: Tremaril® (Wander)
J: Atosil® (Teisan)
Cholinfall® (Tokyo Tanabe)
Dalpan® (Grelan)
Methyloxan® (Nippon Shoji-Kodama) Thioperkin® (Hokuriku)
USA: Trest® (Dorsey)
Metoclopramid
364-52-5
7232-21-5 Hydrochlorid 54143-57-6 Hydrochlorid-Monohydrat
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