- ..
( ):
Acediasulfon
(Acediasulfon-Natrium; Acediasulfone Sodium)
80-03-5
127-60-6
Na-Salz
Chemotherapeuticum
A'-p-sulfanilylphenylglycine sodium
H2N—^ SO2—ft — NH2 + C1-CH2-C00H
Diaminodiphenylsulfon (Dapson. S. 267)
Chloressigsaure
[pH 9]
H2N-(^)— S02-NH -CH2 -C00H Acediasulfon
CH-P 254 803 (Cilag; Anm. 1946).
CH-P 278 482 (Cilag; Anm. 1949).
USP2589211 (Parke-Davis; ert. 1952; Anm. 1948). USP2454835 (Parke-Davis;ert. 1948;Prior. 1943). USP 2 751 382 (Cilag; ert. 1956; D-Prior 6.7.1953).
D: Ciloprin® (Cilag-Chemie)-Komb.
Acefyllin, Acepifyllin 652-37-9 Acefyllin Cardiotonicum,
11__18833-13-1 Acepifyllin Diureticum,
Acefyllin-Heptaminol 59989-20-7 Acefyllin-Heptaminol Broncholyticum
(Acefyllline de piperazine; Heptaminol-acefyllinat)
* 7H-purine-7-acetic add, l,2,3,6-tetrahydro-l,3-dimethyl-2,6-dion, compd. with piperazine (2:1)
*7H-purine-7-acetic add, l,2,3,6-tetrahydro-l,3-dimethyl-2,6-dion, compd. with 6-amino-2-methyl-2-heptanol (1:1)
Acefyllin - Acepifyllin - Acefyllin-Heptaminol - Acemetacin A 3
*SAt4
o^nJ-n
I
CH3
Theophyllin
CI-CH2-COOH
Chioressigsaure
CH2-COOH
ИзС'"\\
I
CH3
Theophyllin - 7 - essigsaure = Acefyilin
I Acepifyllin I
J. Blaisse, Bull. Soc. Chim. Fr. 1949, 769.
D: Etaphydel® (Delalande)-Acepifyllin F: Cariamyl (Carrion)-Acefyllin-Heptammol Chymaphylline (Nicholas)-Acepifyllin Corophylline (Gerda)- Acefyllin-Heptaminol fitaphylline (Delalande)-Acepifyllin
GB:
I:
Eusod (Leo)-Acepifyllin-Komb. Myodel (Clin Midy) -Acefyllin-Heptaminol-Komb. Etophylate® (Delalande)- Acepifyllin Coldrug® (Jamco)-Komb.
Acemetacin
53164-05-9
Antiphlogisticum
l-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ester with glycolic acid a
^nh-nh2
„-O'
w
4~Methoxyphenylhydrazm
* НзС-СО-СН2-СНг~СОО-СН2-СОО-СН2 Lavulmoyloxyessigsaurebenzylester
CH3
H3C0
.-O'1
.NH —N = C
CH2-CH2-COO-CH2
-COO-CH^Q
H3C0‘
JL^_CH3
CH2 - COO - CH2 -COO - CH2^}
(5- Methoxy-2-methyl-3-indolyl-acetoxy I - essigsaurebenzylester
=■-0-
COCl/NaH/DMF
4-СМогвпму1-
cfilorid
C*
I
Г ^“СНз
сн2 - COO - CH2- СО0 - СН2
[l-{4-Chlorbenzoyl)-5-methoxy-2-methyl -
3-indolylacetoxyj-essigsaurebenzylester
Н3СО
H2/Pd-C/CHiCQQH
■-О
4 A Acemetacin - Acenocoumarol
CH2-COOH
Indometacin (S. S. 488)
Br~CH2-COO-CH2
Bromessigsaurebenzylester
СН2-СОО-СН2-СОО-СНг
■<}
Hj/Pd—С/СНэСООН
DOF2,423 (1977).
DOS 2 234651 (Tropon; Anm. 14.7.1972).
FP 2 192 828 (Tropon; Ашп. 13.7.1973; D-Prior. 14.7.1972).
D: Rantudil® (Tropon)
Acenocoumarol
(Acenocumarin;
Nicoumalone)
152-72-7
Antikoagulans
3-(a-Acetonyl-p-nitrobenzyl-4-hydroxycoumarin
COOCH3
Acet-
anhydrid
Salicylsaure-
methylester
O-CQ-CH3
ОС
^^СООСНз
Acetyisalicyisaure-
methylester
[ 2-Acetoxybenzoesaure-methylester)
0^0
OH
4-Hydroxy-
cumarin
CH—
II W
CH-CO-CH3
4-Nitrobenzat-
aceton
OQCch_q_n02
0H CH2-CO-CH3
Acenocoumarol
USP 2 648 682 (Geigy; ert. 1953; CH-Prior. 1950).
D: Sintrom® (Geigy) I: Sintrom® (Geigy)
F: Sintrom® (Geigy) J: Sintrom® (Ciba-Geigy-Fujisawa)
GB: Sinthrome®(Geigy) USA: Sintrom®(Geigy)
Acepromazin - Aceprometazin - Acetarsol A 5
Acepromazin 61-00-7 Neurolepticum,
3598-37-6 Maleat Antiemeticum
10-[3-(dimethylamino)propyl]phenothiazin-3-yl methylketone
2-Acetyl-
phenothiazin
I
CH3
CH3
C1-CH2-CH2-CH2-N
3-Dimethylamtno-
propylchlorid
NaNH2
CH3
Natriumamid
N"
I
CH2
CH2 I /
ch2-n^
c'
I
CH3
СНз
CH3
Acepromazin
DBP 1 049865 (Bayer; Anm. 7.9.1955).
J. Schmitt et al., Bull. Soc. Chim. Fr. 1957, 938,1474.
F: Noctran® 10 (Oin-Comar-Byla)-Komb. Plegicil® (Gin-Comar-Byla)
Plebal® (Fujinaga-Sankyo)-Komb.
Aceprometazin
13461-01-3
Neurolepticum,
Antitussivum
10-[2-(dimethylamino)propyl]phenothiazin-3-yl methylketone
2 - Acetyl-phenothiazm
c-°
I
СНз
CH3
а-СНг-СН-N
СНз СНз
2-Dimethytamino-
propyichtorid
DBP 1 049865 (Bayer; Anm. 7.9.1955).
NaNH2
H3C
If В
‘N^
i
CH2 I
N-CH H3C7 СНз Aceprometazin
D: Clindorm® (Mack, Ulert.)-Komb. F: Mepronizine® (Clin-Comar-Byla)
Noctran® 10 (Clin-Comar-Byla)-Komb. Supponizine® (Clin-Comar-Byla)-Komb.
AcetarSOl 97-44-9 Arsen-Chemo-
(Acetarsone) 5892-48-8 Na-Salz therapeuticum
(Trichomonacid)
Af-acetyl-4-hydroxy-m-arsanilicacid
6 A Acetarsol - Acetazolamid
NH2
N, Cl”
4-Chlor-
anilin
Na3AsO}/[C>jSOt/NH3]
Natrium-
arsenit
AsO(OH)2
II
Cl
i-Chlor-
phenyl-
arsonsaure
AsO|OH)2
NO2 Cl
i-Chlor-3-
mtrophenyl-
arsonsaure
NaOH I33V.|/100°C
AsO<OH)2
N02
OH
Na2S203 oder Fe/NaOH
N atnum-
dithionit
AsO(OH)2
nh2
OH
4-Hydroxy-3-
mtrophenyl-
arsonsaure
З-Атто-Д-
hydroxyphenyl-
arsonsaure
OH
I
0= As—OH
Acetarsol
G. W. Raiziss u. Gavron, J. Am. Chem. Soc. 43, 583 (1921).
G. W. Raiziss u. В. C. Fisher, J. Am. Chem. Soc. 48,1323 (1926).
DRP 250 264 (H. Bart; Anm. 1910).
DRP245 536 (Hoechst; Anm. 1911).
DRP 224 953 (Hoechst; Anm. 1909).
F: Sanogyl (Villette) I: Gynoplix® (Vaillant)
