Атлас Гематология - Андерсон Ш.
ISBN 5-98657-009-Х
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DOT 12, 9(1976).
GB-P 1 246 141 (P. u. B. Coirre; Anm. 30.8.1968; F-Prior. 14.9.1967 u. 16.5.1968).
DAS 1 795 327 (S.A.R.L. Franco-Chimie; Anm. 13.9.1968; F-Prior. 14.9.1967,16.5.1968). DOS 2 139476 (P. u. B. Coirre; Anm. 6.8.1971).
D: <V-Acetyl-L-hydroxyproJin F: JonctumВ® (Merrell)
(Chephasaar)
Oxacillin
(Sodium Oxacillin)
66-79-5 Antibioticum 7240-38-2 Na-Salz-Monohydrat
(5-methyl-3-phenyl-4-isoxazolyl)penicillin or 3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazole-carboxamido)-7-oxo-4-thia-l-azabicyclo[3.2.0]heptane-2-carboxylicacid
(^CHO
h2noh
Benzatdehyd Hydroxyl -
amin
CH = N-Benzaldoxim
\=/ \N
Benzhydroximsaure-
chlorid
Н3С-СО-СН2-СООСгН5 /МаОСНз
)
Acetessigsaureethylester
РЎРћРћРЎРіРќР‘
CO-Cl
“ Tfx /NaHC03 (Г • СНэ COOH
-В»-
5-Aminopenicillan-
saure
COOH
Thionyl-
crtJorrd
5-Methyl-3-phenyl-
isoxazol-4-carbon-
saure
H H
,C0-NH-j—t'SV,CH3
J—]^'АсНз'
tOOH
%^ch3 В°'
Oxacillin
Oxacillin - Oxaflozan - Oxaflumazin Рћ 663
DOT 1,115(1965).
USP 2 996 501 (Beecham; ert. 15.8.1961; GB-Prior. 31.3.1960).
GB-P 905 778 (Beecham; Anm. 31.3.1960; Laufzeit ab 14.3.1961).
GB-P 958 478 (Beecham; Anm. 28.2.1963; USA-Prior. 13.3.1962).
D: CryptocillinВ® (Hoechst) J: Staphcillin VВ® (Banyu)
StapenorВ® (Bayer) USA: BactocillВ® (Beecham-MassengiH) F: BristopenВ® (Bristol) ProstaphlinВ® (Bristol)
I: PenstaphoВ® (Bristol)
Oxaflozan 26629-87-8 Antidepressivum
26629-86-7 Hydrochlorid
4-isopropyl-2-(a,a,a-trifluoro-tti-tolyl)morpholine
Cl-CH2-CH2-0-CH = CH2 + Br2 2-Chlorethylvmylether Brom
Br
I
Cl-CH2-CH2-0“CH-CH2-Br
{2-Chloretboxyj-1,2-dibromethan
3-Tnfluormethy(-
phenyl-magnesium-
bromid
'ChT CH2
CH2 ch.
Br Cl
H2N—CH(CH3)2 / Toluol; Л , Isopropytamin
1-Brom-2-{2-chlorethoxy)-
2-{3-trifluormethylphenyl)-ethan
F3C
I
РЎРќ-РЎРќР·
РЎРќР·
Oxaflozan
DOF 3, 667 (1978); 4, 690 (1979).
DOS 1910 477 (CERM; Anm. 1.3.1969; F-Prior. 4.3.1968,29.5.1968,18.6.1968, 27.8.1968,
15.11.1968.19.2.1969).
USP 3 637 680 (CERM; ert. 25.1.1972; F-Prior. 4.3.1968, 29.5.1968,18.6.1968, 27.8.1968,
15.11.1968.19.2.1969).
N. Busch et al., Eur. J. Med. 11, 201 (1976).
1: ConflictanВ® (Lab. Riom)
Oxaflumazin
16498-21 -8
41761-40-4 Hydrogensuccinat
Psychosedativum
10-[3-[4-(2-m-dioxanylethyl)-l-piperazinyl]propyl]-2-(trifluoromethyl) phenothiazine
+ CI-CH2-CH2
Рѕ
CH2-CH2-CH2-N
10 - (3-Piperazmopropyl)-2-tnf luor -
methylphenothiazin
(vgl. Fluphenazin-Synthese. S. 423}
2-(2-Chiorethyl)-1,3-
dioxan
(aus Acrolein, 1,3-Propandiol
und HCl)
664 Рћ Oxaflumazin - Oxandrolon - Oxazepam
CHz — CH2 — CH2-N N-
O-
Oxaflumaz/n
DAS 1 620281 (Roussel-Uclaf; Anm. 28.6.1965; F-Prior. 29.6.1964,28.9.1964). R. Ratouis u. J. R. Boissier, Bull. Soc. Chim. Fr. 1966,2963.
Alternativ-Syn these:
DOS 1 911719 (S.I.F.A.; Anm. 7.3.1969; F-Prior. 8.3.1968).
F: OxaflumineВ® (Diamant)
Oxandrolon 53-39-4 Anabolicum
17/3-hydroxy-17-methyl-2-oxa-5a-androstan-3-one
OH
OH
17/?-Hydroxy-17a-methyl-
3-oxo-1-androsten
Bleitetraacetat /Osmium-tetroxid
Natrium-
borhydrid
USP 3 128 283 (Searle; ert. 7.4.1964; MEX-Prior. 10.5.1961). R. Pappo, C. J. Jung, Tetrahedron Lett. 1962,365. Ausgangsverbindung:
R. E. Counsell et al., J. Org. Chem. 27,248 (1962).
I: LonavarВ® (Searle)
J: VasoromeВ® (Kowa)
USA: AnavarВ® (Searle) LonovarВ® (Searle)
Oxazepam 604-75-1 Tranquilizer
7-chloro-l,3-dihydro-3-hydroxy-5-phenyl-2H-l,4-benzodiazepin-2-one
Oxazepam - Oxeladin Рћ 665
6-Chlor-2-chlormethyl-
A-phenyt-chinazolin-
3-oxid
(vgl. Chlordiazepoxid-Synthese, S. 188}
7-Chlor-5-phenyl-
2-oxo-l,2-dihydro-
3W-1,4-benzodiazepin-
4-oxid
DOT 1,102 (1965); 9,238 (1973).
USP 3 176 009 (American Home Products; ert. 30.3.1965; Prior. 5.3.1962).
USP 3 296 249 (American Home Products; ert. 3.1.1967; Anm. 4.6.1963; Prior. 29.8.1961, 5.3.1962). DBP 1 445 412 (American Home Products; Anm. 17.8.1962; USA-Prior. 29.8.1961, 5.3.1962).
DBP 1 795 509 (American Home Products; Anm. 17.8.1962; USA-Prior. 29.8.1961, 5.3.1962).
S. C. Bell et al., J. Org. Chem. 27,562 (1962).
S. C. Beil, S. J. Childress, J. Org. Chem. 27, 1691 (1962).
Alternativ-Synthese:
DBP 1 295 563 (American Home Products; Anm, 21.5.1964; USA-Prior. 29.5.1963,13.8.1963).
DBP 1 300 114 (American Home Products; Anm. 21.5.1964; USP-Prior. 29.5.1963,13.8.1963, 3.12.1963,7.5.1964).
DBP 1 543 325 (American Home Products; Anm. 21.5.1964; USA-Prior. 29.5.1963, 31.8.1963,
3.12.1963, 7.5.1964).
DAS 1 795 231 (American Home Products; Anm. 21.5.1964; USA-Prior. 29.5.1963,13.8.1963,
3.12.1963, 7.5.1964).
S. C. Bell et al., J. Org. Chem. 33,216 (1968).
D:
F:
GB:
I:
AdumbranВ® (Thomae)
OvaribranВ® (Thomae)-Komb.
PersumbranВ® (Thomae)-Komb.
PraxitenВ® (Wyeth)
Tranquo-BuscopanВ® (Boehringer Ing.)-Komb. SerestaВ® (Wyeth-Byla)
Serenid-DВ® (Wyeth)
AdumbranВ® (Boehringer Ing.)
IsochinВ® (Tosi)
LimbialВ® (Chiesi)
QuenВ® (Ravizza) QuilibrexВ® (Isnardi) SedokinВ® (Gegmonat) SerpaxВ® (Wyeth)
J: HilongВ® (Banyu)
WakazepamВ® (Wakamoto) USA: SeraxВ® (Wyeth)
