Трансформированная клетка - Эш Б.Б.
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Ага—С и гидроксимочевина. Это возможно при последовательной обработке МГБГ и гидроксимочевиной культивируемых клеток ЗТЗ и SV3T3 (Rupniak, Paul, 1980). Эти исследования иллюстрируют возможность избирательного уничтожения опухолевых клеток в результате использования биохимической основы, отражающей различия регуляции полиаминами клеточного цикла нормальных и трансформированных клеток. Было бы интересно узнать, окажутся ли полезными эти результаты для разрабатывающихся методик терапии злокачественных заболеваний человека.
8.7. УКАЗАТЕЛЬ ЛИТЕРАТУРЫ
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Fausto N*, Butcher F. Я. (1976). Cyclic nucleotide levels in regenerating Ifver. Biochim. Biophys. Acta 428, 702—706.
Fillingame R. H.t Jorstad С. MЛ/orm Z>. /?. (1975). increased cellulai levels of spermidine or spermine are required for optimal DNA synthesis in lymphocytes activated by concanavalin A. Proc. Natl. Acad. Sci. U. S. A. 72, 4042— 4045.
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