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Иммунология. Том 2 - Дэвид Г.

Дэвид Г., Томас Дж. Иммунология. Том 2 — М.: Мир, 1987. — 456 c.
ISBN 5-03-000497-1
Скачать (прямая ссылка): immunologiyat21988.djvu
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Наконец, вполне возможно, что контролируемый генами /г иммунный ответ лежит в основе ассоциации определенных патологий человека и животных с гаплотипом главного комплекса гистосовместимости [61]. Более полное понимание механизмов /r-генного контроля может помочь разработке подходов к профилактике и лечению таких нарушений.
ЛИТЕРАТУРА
1. Schwartz R. Н. Functional properties of I region gene products and theories of immune response (Ir) gene function. In: la Antigens, Vol. I: Mice, ed. by S. Ferrone and C. S. David, pp. 161—218, CRC Press, Boca Raton, Florida, 1982.
2. Benacerraf B., Green I., Paul W. E. The immune response of guinea pigs to hapten-poly-lysine conjugates as an example of the genetic control of the recognition of antigenicity, Cold Spring Harbor Symp. Quant. Biol., 32, 569 (1967).
3. Ellman L., Green /., Martin W. J., Benacerraf B. Linkage between the PLL gene and the locus controlling the major histocompatibility antigen in strain 2 quinea pigs, Proc. Natl. Acad. Sci. USA, 66, 322 (1970).
4. Bluestein H. G., Green /., Benacerraf B. Specific immune response genes of the guinea pig. II. Relationship between the poly-L-lysine gene and the genes controlling immune responsiveness to copolymers of L-glutamic acid and L-tyrosine in random-bred Hartley guinea pigs, J. Exp. Med., 134, 471 (1971).
5. McDevitt Н. О., Sela М. Genetic control of the antibody response. II. Further analysis of the specificity of determinant-specific control,‘and genetic analysis of the response to (H, G)-A — L in CBA and C57 mice, J. Exp. Med., 126, 969 (1967).
6. McDevitt II. O., Deak В. D., Shreffler D. С., Klein J., Stimpfling J. H., Snell G. D. Genetic control of the immune response. Mapping of the Ir-1 locus, J. Exp. Med., 135, 1259 (1972).
7. Dorf М. E., Benacerraf B. Complementation of Н-2-linked Ir genes in the mouse, Proc. Natl. Acad. Sci. USA, 72, 3671 (1976).
8. Lieberman Я., Paul W. E., Humphrey W., Stimpling J. H. H-2 linked immune response (Ir) genes: Independent loci for Ir-IgG and Ir-IgA genes, J. Exp. Med., 136, 1231 (1972).
9. Baxevenis C. TV., Nagy Z. A., Klein J. A novel type of T-T cell interaction removes the-requirement for I-В region in the H-2 complex, Proc. Natl. Acad. Sci. USA, 78, 3809 (1981).
10. Longo D. L., Paul W. E. Immune response genes and la antigens. The relatihonsips between them and their role in lymphocyte interaction. In: Histocompatibility Antigens, ed. by P. Parham and J. L. Strominger, p. 159, Chapman and Hall., London, 1982.
11. Mitchell G. E., Grumet F. СMcDevitt H. O. Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L-(Tyr, Glu)-poly-D-L-A!a-poly-L-Lys, J. Exp. Med., 135, 126 (1972).
12. Bottomly K., Maurer P. II. Antigen-specific helper T cells required for dominant production of an idiotype (Thld) are not under immune response (Ir) gene control, J. Exp. Med., 152, 1571 (1980).
13. Paul W. E., Benacerraf B. Functional specificity of thymus-dependent lymphocytes, Science, l'»5, 1293 (1977).
14. Heber-Katz E., Hansburg D., Schwartz В. H. The la molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation, J. Mol. Cell. Immunol, (in press), 1983.
15. Waldron J. A., Horn R. G., Rosenthal A. S. Antigen-induced proliferation of guinea pig lymphocyte in vitro: Obligatory role of macrophages in the recognition of antigen by T-lymphocytes, J. Immunol., Ill, 58 (1973).
16. Schwartz R. Д., Yano A., Paul W. E. Interaction between antigen-presenting cells and primed T lymphocytes: An assessment of Ir gene expression in the antigen-presenting cell, Immunol. Rev., 40, 153 (1978).
17. Steinman R. М., Witmer M. D. Lymphoid dendritic cells are potent stimulators of the primary mixed leucocyte response in mice, Proc. Natl. Acad. Sci. USA, 75, 5132 (1978).
18. Stingl G., Katz S. /., Clement L., Green /., Shevach E. M. Immunologic functions of la-bearing epidermal Langerhan’s cells, J. Immunol., 121, 2005 (1978).
19. Glimcher L. H., Kim K. JGreen I., Paul W. E. Ia antigen bearing В cell tumor lines can present protein antigen and alloantigen in an МНС-restricted fashion to antigen-reactive T cells, J. Exp. Med., 155, 445 (1982).
20. Chesnut R. W., Grey II. M. Studies on the capacity of В cells to serve as antigen-presenting cells, J. Immunol., 126, 1075 (1981).
21. Sredni B., Matis L. A., Lerner E. A., Paul W. E., Schwartz R. H. Antigen-specific T cell clones restricted to unique F, major histocompatibility complex determinants. Inhibition of proliferation with a monoclonal апи-1а-ал1г!^у, J. Exp. Med., 153, 677 (1981).
22. Kimoto M.,\ Fathman C. G. Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A-region gene products function effectively in antigen-presentation, J. Exp. Med., 152, 759 (1980).
23. Jones P. P., Murphy D. B., McDevitt H. O. Two-gene control of the expression of a murine Ia antigen, J. Exp. Med., 148, 925 (1978).
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